Treatment methods · stem cells
Below — without scientific jargon — we explain which cells we use, how we deliver them, who benefits, and when this therapy is not right.
In brief · one minute read
Stem cells are the body's universal "repair" cells. Unlike ordinary heart, liver or muscle cells, they have not yet committed to a single role.
When an organ is damaged — by a stroke, a heart attack or diabetes — a stem cell can become the tissue type that's needed and help recovery. At the same time it reduces inflammation and reactivates the body's own "dormant" cells.
We use young stem cells together with their signalling particles — exosomes. We deliver them to the right part of the body in five different ways and choose the route that works best for the specific diagnosis.
Three sources of cells
Three types of biomaterial with different mechanisms of action. The specific choice depends on the diagnosis and is selected individually.
The youngest and most active cells. Suitable for most patients — they hardly trigger an immune reaction, because they are not yet "marked" by age.
In plain words
Where from
From the tissue of the umbilical cord of healthy newborns — after a planned caesarean section and with the parents' written consent.
What it does
Differentiates into the needed tissue, reduces inflammation, and reactivates the body's own cells.
Where it goes
Into the bloodstream via an IV drip, or into the cerebrospinal fluid via a thin needle.
Young multipotent cells isolated from Wharton's jelly of the umbilical cord. High proliferative activity and low immunogenicity.
Most effective in autoimmune conditions — where the immune system attacks the patient's own tissues.
In plain words
Where from
From the placenta immediately after birth — normally the placenta is discarded; we use it for medical purposes.
What it does
Strongly calms an over-active immune system and reduces autoimmune aggression.
Where it goes
Mostly into the bloodstream via an IV drip in systemic inflammatory conditions.
Placenta-derived cells with pronounced immunomodulatory potential. Used in autoimmune and inflammatory conditions.
A modern non-invasive route — therapy can continue at home between procedures.
In plain words
Where from
These are not cells but tiny "messages" sent out by stem cells — about 200 times smaller than a cell.
What it does
They carry signalling molecules that "instruct" the body's cells how to repair themselves.
Where it goes
Uniquely — as nasal drops they enter the brain directly through the nose, bypassing barriers.
Extracellular vesicles 30–150 nm in size carrying signalling molecules. Capable of crossing the blood-brain barrier.
Map · where each method works
Stem cells can be administered in different ways — through the bloodstream, into the cerebrospinal fluid, directly into a damaged joint, or as nasal drops. The route is chosen by the physician based on the diagnosis, the goal of treatment, and the patient's condition.
Cells travel throughout the body via the bloodstream. The most studied and broadly applicable route. Suitable for most diagnoses.
More belowA thin needle in the lower back under local anaesthesia — cells reach the brain and spinal cord directly. Used for cerebral palsy, stroke, Parkinson's disease.
More belowA direct injection into the affected joint, muscle or damaged tissue. When the highest cell concentration is needed in one zone — for example, knee osteoarthritis.
More belowThrough the olfactory nerve, the "messages" from cells reach the brain — no needle, no hospitalisation. Therapy can continue at home between procedures.
More belowAn IV drip plus a spinal injection in one trip — for severe neurological cases. Prescribed by the academic board.
More belowFive routes of administration
From systemic intravenous infusion to precise intrathecal delivery into the CNS. The route is dictated by the diagnosis, not by preference.
The most studied and widely used route. Cells distribute throughout the body via the bloodstream, delivering a powerful systemic effect.
What the terms mean
What to know
Cells are injected directly into the subarachnoid space via lumbar puncture. The goal is to bypass the blood-brain barrier and deliver cells into the central nervous system.
What the terms mean
What to know
Direct injection into a specific organ or damaged tissue. Used when maximum cell concentration in the affected area is required.
What the terms mean
What to know
An advanced non-invasive method. Exosomes pass through the olfactory and trigeminal nerves directly into the brain — no needle, no hospitalisation, delivered as nasal drops.
What the terms mean
What to know
A combination of two routes for maximum effect. Most often intravenous administration for systemic support plus intrathecal for direct CNS impact.
What the terms mean
What to know
These technologies operate under the oversight of regulators on three continents.
NMPA filing
NMPA Drug Application Acknowledgement — umbilical-cord MSC injection
ANSM · France
ANSM (France) Clinical Trial Authorization
ISO 9001:2015
ISO 9001:2015 — Bureau Veritas (English version)
Six clinical fields
Six main areas where Hanshi United has accumulated experience. Every case is reviewed individually by the academic board.
Who it suits
For patients after a stroke and those with cerebral palsy, autism, Parkinson's or Alzheimer's disease.
The most common application of cell therapy. Stem cells and exosomes help restore nerve cells, reduce inflammation in the brain, and improve connections between neurons. They are particularly effective when intravenous and spinal delivery are combined.
Who it suits
For patients with myocardial infarction, ischaemic heart disease, or heart failure.
Myocardial infarction, ischaemic heart disease, heart failure, dilated cardiomyopathy
Who it suits
For patients with Type 1 or Type 2 diabetes, particularly when early complications appear.
Type 1 and Type 2 diabetes, diabetic complications
Who it suits
For patients with liver fibrosis or cirrhosis, Crohn's disease, or ulcerative colitis.
Liver cirrhosis and fibrosis, liver failure, Crohn's disease, ulcerative colitis
Who it suits
For patients with osteoarthritis, avascular necrosis, or fractures that heal slowly.
Osteoarthritis, avascular necrosis of the femoral head, osteoporosis, delayed fracture healing
Who it suits
For patients with lupus, rheumatoid arthritis, scleroderma, or severe psoriasis.
Systemic lupus erythematosus, rheumatoid arthritis, psoriasis, scleroderma
Detailed information on each diagnosis is available in the Treatments section.
Important · Contraindications
The conditions below either preclude cell therapy or require particular caution. The final decision is made by a physician after a full examination.
Stem cells can stimulate the growth of existing tumours through growth factors and angiogenesis.
What to do
First complete the full course of oncology treatment and achieve stable remission (typically 5+ years). After that we are ready to review your case — cell therapy can speed up recovery after chemotherapy or radiotherapy.
During an active infection, cell therapy can worsen the condition and reduce the effectiveness of the body's own immune response.
What to do
Wait until you have fully recovered and your test results have returned to normal. This is a matter of weeks, not years — once you have recovered, the contraindication no longer applies and we can begin therapy.
The effect of stem cell therapy on the foetus and the breastfed infant has not been studied in clinical trials.
What to do
There is no safe alternative during pregnancy — but after the birth and the end of breastfeeding you are welcome to contact us again.
Any injectable cell-administration route carries a bleeding risk when haemostasis is impaired. Prior correction is required.
What to do
First we correct haemostasis together with a haematologist — this usually takes 1–3 months. Once the blood markers normalise, injectable routes become safe.
Tell us your story — the academic board will review your questionnaire and within 24-48 hours will draft a personal plan: which cells, which route, and what course.
Medical questionnaire · 10–15 min
If you are ready to share the medical history and documents in advance, please fill out the detailed questionnaire. This helps the academic board prepare a personal protocol before the first conversation.
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