Methods of administration / 03

How living cells reach the body

There is no "one shot for all". The choice of administration route is a key clinical decision. Systemic effect via the bloodstream, direct delivery into the CNS or targeted local injection — our academic board selects the optimal protocol for your diagnosis.

Cell types

What we administer

Three types of biomaterial with different mechanisms of action. The specific choice depends on the diagnosis and is selected individually.

Administration routes

Five routes of administration

From systemic intravenous infusion to precise intrathecal delivery into the CNS. The route is dictated by the diagnosis, not by preference.

  1. 01

    Intravenous (systemic) administration

    The most studied and widely used route. Cells distribute throughout the body via the bloodstream, delivering a powerful systemic effect.

    What to know

    • Immunomodulation and reduction of inflammatory processes
    • Activation of the body's dormant stem cells
    • Suitable for autoimmune, endocrine and cardiovascular conditions
    • Course of 3 procedures spaced 15–20 days apart
    UC-MSCP-MSC
  2. 02

    Intrathecal administration into the CNS

    Cells are injected directly into the subarachnoid space via lumbar puncture. The goal is to bypass the blood-brain barrier and deliver cells into the central nervous system.

    What to know

    • Cells reach the CNS directly, bypassing the blood-brain barrier
    • Critical for cerebral palsy, autism, developmental delay, Parkinson's and Alzheimer's
    • Used for stroke recovery and traumatic brain injury
    • The procedure takes 30–45 minutes under local anaesthesia
    UC-MSC
  3. 03

    Local (targeted) administration

    Direct injection into a specific organ or damaged tissue. Used when maximum cell concentration in the affected area is required.

    What to know

    • Intra-articular — for osteoarthritis and joint disorders
    • Localised injection — for spinal cord injuries
    • Intramuscular — for muscle tissue recovery
    • Targeted regenerative effect in a specific area
    UC-MSCP-MSC
  4. Innovation
    04

    Nasal exosomes

    An advanced non-invasive method. Exosomes pass through the olfactory and trigeminal nerves directly into the brain — no needle, no hospitalisation, delivered as nasal drops.

    What to know

    • Safe direct entry into the brain via neural pathways
    • Nerve cell regeneration and suppression of neuroinflammation
    • Therapy can continue at home between procedures
    • Complements intrathecal administration or used on its own
    Exosomes
  5. 05

    Combined therapy

    A combination of two routes for maximum effect. Most often intravenous administration for systemic support plus intrathecal for direct CNS impact.

    What to know

    • Most effective approach for severe neurological disorders
    • Systemic immunomodulation plus direct CNS regeneration
    • Dosage and intervals are calculated individually
    • Prescribed by the academic board based on diagnostic findings
    UC-MSCP-MSCExosomes

Indications

Where these methods apply

Six main areas where Hanshi United has accumulated experience. Every case is reviewed individually by the academic board.

Detailed information on each diagnosis is available in the Treatments section.

Important · Contraindications

When cell therapy is NOT applied

The conditions below either preclude cell therapy or require particular caution. The final decision is made by a physician after a full examination.

Is this suitable for your case?

A free consultation — send your case, and the academic board will provide a preliminary assessment and recommend an optimal administration route.

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