Anamnesis
Tóng Mǒupíng, male, age 50, type 2 diabetes for 5+ years, on oral hypoglycemic therapy (metformin 2 tablets twice daily), postprandial blood glucose no lower than 12.0 mmol/L. Recent weight loss of ~5 kg, difficulty falling asleep, light sleep, frequent night-time waking.
Treatment plan
September 2023: perinatal NK immune cells 2U single dose + umbilical cord mesenchymal stem cells (UC-MSC) 6U IV ×3 administrations, monthly interval.
- Therapy
- NK perinatalUC-MSC (umbilical cord MSC)
- Delivery route
- Intravenous (IV)
Outcome
After one course of stem cell therapy, serum insulin rose from 6.81 µIU/mL to 8.94 µIU/mL — indicating improved β-cell function. Oral hypoglycemic dose reduced to 1 tablet twice daily. Postprandial blood glucose stable within normal range, general status improved, body weight gain 2 kg, facial skin tone restored, increased work capacity, marked improvement in sleep quality.
Laboratory tests (before / after)
Insulin before treatment
| Test | Result | Unit | Reference |
|---|---|---|---|
| Serum insulin | 6.81 | µIU/mL | 3.00-25.00 |
- Summary: no abnormalities
- Test date: 2023-09-27
Insulin after treatment
| Test | Result | Unit | Reference |
|---|---|---|---|
| Serum insulin | 8.94 | µIU/mL | 2.2-25.00 |
- Test date: 2023-12-27
Physician conclusion
Stem cell transplantation promotes regeneration of pancreatic islet β-cells, protects endogenous β-cells from apoptosis, improves insulin resistance, and lowers the risk of diabetes-related side effects.
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