Anamnesis
Yú**, male, age 66. Admitted on 2020-10-30 to the First Affiliated Hospital of Nanchang University (南昌大学第一附属医院). Received anti-infective and hepatoprotective therapy. During 28-day ICU stay, condition remained critical. Discharged 2020-12-07 against medical advice. Diagnoses: carbapenem-resistant Acinetobacter baumannii, Klebsiella pneumoniae infection, pulmonary aspergillosis, severe pneumonia, encephalopathy, chronic bronchitis with emphysema, bilateral pleural effusion, sinusitis, sinus tachycardia, hypoalbuminemia, anemia, hepatic insufficiency, electrolyte imbalance, arrhythmia. (Subsequently confirmed as lung cancer in expert consultation.)
Treatment plan
Adult donor NK immune cells, 1U intravenous infusion, two consecutive administrations with a 1-month interval.
- Therapy
- NK adult
- Delivery route
- Intravenous (IV)
Outcome
At follow-up on 2021-04-08, the patient was in good condition with occasional cough, normal diet and bowel function, ambulating independently, fully self-care.
Physician conclusion
No significant adverse reactions. NK cells, as an important component of innate immunity, play a meaningful role in anti-tumor immunity.
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